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Someone who drops two pant sizes while the scale moves slowly is succeeding, regardless of what arbitrary number they expected to see

Both Use Gradual Dosing, But Tirzepatide Offers More Flexibility Semaglutide uses a fixed, stepup approach: Treatment begins with a low starting dose, which is gradually increased over several weeks

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The article links dehydration risk to reduced oral intake and to concurrent illness, both of which compound the effect of nausea, vomiting, and general gastrointestinal disturbance during titration