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Yes, and that partly explains why injections get so much attention

Monitoring Progress Effectively: Rather than relying solely on scale weight, which can be misleading due to muscle preservation and fluid fluctuations, comprehensive progress tracking should include body composition analysis (DEXA scan, bioelectrical impedance, or skinfold measurements), circumference measurements (waist, hips, thighs, arms), progress photos taken in consistent lighting and positioning, and subjective measures like energy levels, appetite patterns, and how clothing fits

Pawelczyk, J

Health 1 , 2 (2024)

A study in a respected medical journal found that the Vitamin B12 type chosen can greatly affect treatment success