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Whilst many patients experience minimal symptoms, others may find digestive effects more troublesome, particularly during initial treatment or dose escalation

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An embodiment of present invention provides a process for purification of compound of forumula-13, comprising subjecting a solution of compound of formula- 13 to RP-HPLC purification by using buffer solution as mobile phase- A and acetonitrile as mobile phase-B

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The study was conducted in accordance with the Declaration of Helsinki of 1964 and its later amendments and International Council for Harmonisation (ICH) Good Clinical Practice guidelines