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Semaglutide commonly causes nausea, vomiting, and diarrhoea, particularly during dose escalation

Houghton V, Du Preez A, Lefvre-Arbogast S, de Lucia C, Low DY, Urpi-Sarda M, et al

Concurrently, cAMP/PKA signaling induces autophagic flux and upregulates antioxidant defense mechanisms, facilitating the clearance of damaged organelles and misfolded proteins

However, there are certain situations where supplementation may warrant additional caution or a conversation with a healthcare provider before use