In addition, probiotics can stimulate the hosts antioxidant defence systems and increase the activity of antioxidant enzymes (224)
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These findings contribute to the growing body of literature suggesting that GLP-1based therapies may have applications beyond glycemic control, particularly in the context of hypogonadism related to obesity and insulin resistance
Begum MN, Mahtarin R, Islam MT, Antora NJ, Sarker SK, Sultana N, et al
Clinical studies have demonstrated that GLP-1 receptor agonists can reduce various inflammatory biomarkers , including: C-reactive protein (CRP) : A general marker of systemic inflammation Interleukin-6 (IL-6) : A pro-inflammatory cytokine Tumour necrosis factor-alpha (TNF-) : Another key inflammatory mediator Plasminogen activator inhibitor-1 (PAI-1) : Associated with cardiovascular inflammation The magnitude of these effects varies between studies and may depend on baseline inflammatory status, degree of weight loss achieved, and individual patient characteristics
