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I was hopeful that it would be positive, but Im not surprised that its not, said Zaldy Tan, MD, MPH, director of the Bernard and Maxine Platzer Lynn Family Memory and Healthy Aging Program at Cedars-Sinai Medical Center

Medications are the first-line treatment, with surgery reserved for those who dont respond to medications or cant take them

This leads to the formation of regenerative hepatic nodules encased in dense fibrous tissue, containing significantly higher levels of extracellular matrix proteins, particularly collagen types I, III, and IV, which hinder portal blood flow and elevate portal pressure, ultimately culminating in clinically significant portal hypertension in later disease stages (1)

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Excess adiposity is a pro-inflammatory state associated with increased risk of several types of arthritis, increased arthritis disease activity and/or severity, and poorer response to certain treatments