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For gene expression analysis, 1 g RNA was used for cDNA synthesis using a qScript cDNA Synthesis kit (Quanta Bio, 66196756)

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recently demonstrated that the catalytic activity of AOAA-modified CBS can be rescued in the presence of high concentrations of serine (Figure 4A) ( 50 ) values of 1.1 M and 8.5 M, respectively ( in vivo experiments