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[18] [19] Appetite regulation mechanisms: GLP-1 receptors in the hypothalamus and brainstem mediate satiety signaling

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Specifically, prolactin levels should be considered in obese individuals with typical hyperprolactinemia, including galactorrhea, reproductive or gonadal endocrine dysfunction (such as amenorrhea, oligomenorrhea, infertility, decreased libido, or erectile dysfunction), and symptoms suggestive of sellar lesions (such as persistent headaches, visual field defects, or cranial nerve involvement)