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Weight loss The thought that semaglutide might be used as a weight loss drug dawned during its Phase II trials when it resulted in weight loss in patients with diabetes as well as those with obesity

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Beyond diabetes management, certain GLP-1 receptor agonist medications have demonstrated cardiovascular benefits in clinical trials, though these benefits shouldn't be attributed to endogenous GLP-1 function alone

Ayoub WA, Kumar AA, Naguib HS, Taylor HC