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Thus, it cannot be emphasized enough that understanding the molecular underpinnings of smoking exposure and tobacco consumption will offer invaluable opportunities for enhancing our understanding of lung cancer pathogenesis, and subsequently, the early detection of this morbid malignancy

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For children, exposure to the nicotine in e-liquid products, even in small amounts, could lead to death from cardiac arrest, as well as seizure, coma and respiratory failure

Key hurdles include limited scientific evidence on long-term health effects, potential health risks from harmful chemicals, evolving regulations, consumer skepticism, competition from alternatives like e-cigarettes, and concerns about acting as a gateway to tobacco