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Results: PA administration showed beneficial effects on APAP-induced hepatotoxicity through improvements in liver functions, decreased CYP2E1 gene expression, decreased serum and liver iron load, decreased MDA, increased GSH, increased SIRT -1 expression level and improvement in hepatic architecture

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Indeed, alterations in nucleus accumbens function have been implicated in disorders that are routinely accompanied by motivational impairments (e.g., depression)

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