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Research Applications May Include : Studies on neuroprotection and cognitive function Exploration of BDNF modulation Investigations into stroke recovery and brain injury models

The regulatory pathway for biomarker approval adds additional complexity and delay to clinical implementation (Nisenblat et al., 2016)

Zhang H, Wang Y, Lian L, Zhang C, He Z

Baumgard, PhD, Iowa State University, for providing his expertise and reviewing the final paper, and Alice Mac-Gregor Harvey, NC State College of Veterinary Medicine, for the graphical illustrations in this text

Current treatments (physiotherapy, anti-inflammatory/analgesic medication, surgery) for IVD disease may resolve neurological deficits and reduce pain (although in many cases insufficient), but do not lead to repair of the degenerated disc