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The supernatant of the liver homogenate was diluted to 2.0 mg/ml of protein concentration for the assay

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Although the mechanism of action of bupropion is not fully understood, DAT inhibition is unlikely because four positron emission tomography (PET) scan studies have reported that clinically effective doses of bupropion produce very low occupancy of dopamine reuptake sites [113, 114, 115, 116]

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