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Preterm Birth: Pregnant women who engage in smoking behavior are more susceptible to experiencing preterm birth

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To better assess the chronic effects of exposure to heated tobacco or electronic cigarette smoke on endothelial dysfunction in the brachial artery, we conducted a systematic review (see the flow-diagram in Figure 2, Methods in Supplementary Data) [47]

doi: 10.1111/1467-8624.00401

It's the heat and combustion products that come with smoking