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For documented deficiency, loading doses of 1000 mcg daily or several times weekly for 1 to 2 weeks rapidly restore tissue levels

Additionally, semaglutide should not be used by: Pregnant people People of any sex planning to conceive in the near future Anyone with a personal or family history of certain thyroid cancers, including medullary thyroid carcinoma (MTC) and multiple endocrine neoplasia syndrome type 2 (MEN 2) Phentermine should not be used by people who are pregnant or nursing, who have recently started taking monoamine oxidase inhibitors, or who have: A history of heart problems Hyperthyroidism Glaucoma Agitation A history of substance use disorder Who should not combine semaglutide and phentermine

But in the Ozempic vs phentermine face-off, which works better for weight loss

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Enhanced Efficacy: Its dual mechanism may offer superior glycemic control and weight loss outcomes compared to single-action treatments