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Recognized differences in TRPA1 channels across species have been cited as confounding the translational value of results from preclinical rodent models (160)

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Compliance with ethical standards Clinical Trials Registry: CTRI/2021/01/030204

5 Conclusion This systematic review and meta-analysis indicate that sublingual and oral vitamin B12 administration provide efficacy comparable to intramuscular injection in improving serum cobalamin levels and reducing hyperhomocysteinaemia

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