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Less common side effects included skin tingling and increased heart rate for up to 24 weeks, after which time heart rate declined

Patients receive thorough evaluations, ongoing monitoring, and lifestyle guidance to support sustainable weight loss using FDA-cleared oral semaglutide as part of a comprehensive approach

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Four clusters of patients were identified in this study, characterized by 1) multisystemic symptomatology, 2) POTS-dominant presentation, 3) cognitive and sleep dysfunction with increased pain, and 4) milder symptomatology (Fig