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Activating the HGF/c-Met signaling pathway promotes PNI in pancreatic cancer The crosstalk between cancer cells and nerves plays a vital role in PNI mediated by neurotrophins secreted by cancer cells

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Melatonin has been shown to exert neuroprotective effects through anti-inflammatory and antioxidant actions, reduction of cerebral edema, preservation of cognitive function, and activation of endogenous repair mechanisms (141145)

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5-Methyl THF serves as a methyl donor in the vitamin B 12 -dependent reactions catalyzed by methionine synthase, which remethylates homocysteine to methionine, regenerating THF