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These treatments are not appropriate for all patients and may be contraindicated in individuals with certain medical conditions including hormone-sensitive cancers, blood clotting disorders, severe liver disease, or cardiovascular conditions

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A 2024 study in dexamethasone-induced NASH rats demonstrated that L-carnitine restored Akt phosphorylation, inhibited FOXO1 nuclear translocation, and downregulated autophagy and apoptosis markers (LC3, P62, caspase-3, p-MLKL) via the Akt/FOXO1 pathway (59)

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