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Multiple molecules participate in the process of ferroptosis by regulating the lipid peroxidation state and cellular iron level [13]

72 hours after the first round of transfection, cells were subjected to CHX chase and harvested for Western blot analysis

While prodrugs, transcytosis, nanoparticle systems, and viruses have ongoing clinical trials, cell-mediated drug delivery is in the preclinical stage 2,85,86,87,88

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With an additional change of the CGFS signature to CSYC, reduction of roGFP2 increased only slightly (approximately to 1.8% of class I HsGRX2), but HED activity was increased more efficiently (approximately to 2.5% of class I HsGRX2) 14