Worsening of renal function was not reported in any of the studies, including PIONEER 5, where T2D patients had established CKD [39,40,41,42,43,44,45,46]
When you stop taking Wegovy , you will stop experiencing the effects of the drug as it flushes out of your system (a process that can take up to 57 weeks )
But as someone who prescribes only legitimate GLP-1 therapies to people with obesity and weight-related metabolic diseases, I need to say this: Microdosing GLP-1s is not a thing
The decrease in urinary 24-h noradrenaline excretion was likely due to weight loss
Long-term efficacy trajectories of GLP-1 receptor agonists: a systematic review and network meta-analysis, Diabetes, Metabolic Syndrome and Obesity (2025) The effect of early response to GLP-1 RA therapy on long-term adherence and persistence among Type 2 diabetes patients in the United States, Journal of Managed Care & Specialty Pharmacy (2019) Weight loss between glucagon-like peptide-1 receptor agonists and bariatric surgery in adults with obesity: A systematic review and meta-analysis, Obesity (2022) FDA approves first medication for obstructive sleep apnea, U.S
