It could be linked to the generation of free radicals by multiple mechanisms, as has been discussed above and the induction of GGT
This is important because the liver uses glutathione to remove harmful substances
Selenoprotein activity is essential to many biological processes, such as fetal development ( Most known selenoproteins are expressed in the neurons of adult mouse brains ( Autism spectrum disorder (ASD) affects 1 in 44 children in the United States ( Selenium and selenoproteins in brain development and function Role of selenium in the brain In a study examining the proportions of total body selenium in individual organs, it was found that 2.4% of total body selenium is found in the brain ( Glutathione peroxidases (GPX1, GPX2, GPX3, GPX4, and GPX6) Glutathione peroxidases (GPx) have a thioredoxin fold that is distinguishable from other selenoproteins, in which there is an alpha helix with a cysteine residue
doi:10.1016/S0140-6736(18)32590-X Zhang W, Liu Y, Ge M
Journal of Diabetes & Metabolic Disorders, 21(1), 4349