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PMID: 26475342

Genetic Predisposition and Your GLP-1 Response: Who Benefits From Which Approach Key genetic variants in GLP1R, GIPR, FTO, and MC4R influence how your body processes hunger signals and metabolic regulation

For example, in a recent study, menopausal women with obesity or overweight lost more weight when tirzepatide was used along with HRT, and they had better cardiometabolic outcomes

Many people reported positive effects, such as reduced anxiety and depression symptoms, increased energy, clearer thinking, and better control over compulsive behaviors like smoking and shopping