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Statistical Analysis: Paired t-tests were used to identify proteins, peptides, and PTMs with significant abundance differences between fresh and stored RBCs

These findings unveil a distinct regulatory axis in which nutrient sensing by astrocytes fine-tunes inflammatory and oxidative responses at the level of protein translation, revealing a novel mechanism by which substrate availability modulates enzyme activity during neuroinflammation 123

Pharmacogenomic considerations may become increasingly important as the peptide field matures

The cytotoxicity of Ru(II)-OH, NP2, and NP4 against 143B and K7M2 cells in a 21% O 2 or 1% O 2 atmosphere was studied using a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay

In the preventive paradigm of the Tg2576 mouse model of AD, TM treatment reduced brain copper levels and lowered A concentrations (91,92)