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Hormone Optimization is a key component to maintaining a high quality of life and improving longevity

Currently the preferred delivery systems are the parenteral or local route, as miRNAs have reduced intestinal absorption via the oral route [78]

Consistency important, benefits develop over 8-12 weeks continued use

Direct inhibition of sympathetic nerve function by reducing the biosynthesis of NE, preventing the conversion of DA to NE in sympathetic nerves, and possibly by increasing the release of DA, can induce renal vasodilation, diuresis, and natriuresis

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