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Acetylation of p53 protein at lysine 120 up-regulates Apaf-1 protein and sensitizes the mitochondrial apoptotic pathway

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Li SL, Ting SS, Lindeman R, Ffrench R, Ziegler JB

1) from 3,4- cis -leucoanthocyanidins ( 2 ) to anthocyanidins ( 3 ) is thought to be catalysed by the Fe/-ketoglutarate-dependent dioxygenase leucoanthocyanidin dioxygenase (LDOX), also called anthocyanidin synthase (ANS) 8,9

Continual synthesis of endogenous glutathione is essential for normal growth and development (20), but the importance of maintaining the correct ratio of reduced:oxidised glutathione in Bd was unknown