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The high prevalence raises questions regarding a potential role in extra-thyroidal diseases

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Pre-cycle testing Before starting IGF-1 LR3, establish baseline values for: Fasting glucose and insulin HbA1c (long-term blood sugar marker) IGF-1 levels Complete metabolic panel Lipid panel These baselines allow comparison during and after cycles to identify any negative trends

To reduce clearance and increase the serum half-life, polyethylene glycol-5000 (PEG5000) was conjugated to the molecule

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