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(2025) The crucial difference between all safer nicotine products and traditional cigarettes is that none of them deliver nicotine to the user through the combustion of tobacco

Apart from the substantial heterogeneity among the studies, involvement of studies with relatively small sample sizes and the direct combination of cross-sectional and prospective studies for synthesizing a common effect size may not be statistically favorable to draw a sound conclusion based on these metaanalyses

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