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Singapore's smoking rate has fallen steadily over the years

state, ensuring elected officials, advocates, and media know who they are and whose advice not to trust on public health

A further limitation of the existing literature is that most population-based studies have classified cigarette smoking and e-cigarette use crudely, often treating e-cigarette use as a binary variable without distinguishing between exclusive e-cigarette users, dual users, and former smokers who no longer use any nicotine product

For example, a recent meta-analysis 42 of 28 randomized clinical trials concluded that bupropion increased the likelihood (by 3.5-fold) of smoking cessation at 3 months, especially at a dose of 300 mg/day, but no significant effect was observed at 6 months