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"This will be a dramatic change in what a cigarette package looks like, no doubt about it," Hamburg said, later adding: "It will change the consumer response to a package of cigarettes, but frankly, that's what we want." Thomas Glynn, director of cancer science and trends for the American Cancer Society, said the old labels have been virtually invisible because they're small and have been around for so long

The letter, she said,"is an extraordinary step for hundreds of concerned health professionals to take