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By stimulating the GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 receptors, Tirzepatide helps achieve more balanced levels of insulin and glucose in the body

In November 2024, Phase II data for MariTide showed that the drug elicited up to 20% weight loss on average at 52 weeks in patients who were overweight or had obesity

TRP-2, tyrosinase-related protein 2

Clinical recommendations based upon the patients renal function include [see Dosage and Administration (2.1, 2.4) and Clinical Pharmacology (12.3)]: Before initiating XIGDUO XR, obtain an estimated glomerular filtration rate (eGFR)

Knowing what not to do is the other half