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artesunate combined with dexmedetomidine downregulated PERK, ATF4, and CHOP expression, reduced iron concentration, and attenuated iron death to ameliorate lung injury in ischemia/reperfusion rats (Xu et al., 2024)

For the primary composite endpoint of myocardial infarction, stroke or all-cause mortality, benchmarking identified high agreement between the reference trials and their emulations for all individual endpoints except for all-cause mortality in SUSTAIN-6, informing subsequent analyses

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