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Chemically, methionine is susceptible to redox reactions, with oxidation requiring the loss of a pair of electrons to form methionine sulfate, i.e., oxidized form (MetSO), which is then reduced by the enzyme methionine sulfoxide reductase to convert it back to methionine

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We should also consider other reasons for acute kidney failure, like dehydration, infections, certain drugs, and sustained immobility

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However, pregnancy and certain health conditions may cause increased excretion of carnitine, which could increase risk of deficiency