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Determination of As-ADI The average daily intake of As through drinking water ingestion was calculated using the following equation [43]: where ADI is expressed as average daily intake of As (mg/kg/day), DWAs is drinking water arsenic concentration (mg/L), IR is daily ingestion rate (L/day) (self-reported by participant), and BW is body weight (kg) (measured during study)

4 The smoking intensity figure of 11.5 cigarettes per day (with a 95% confidence interval for the mean of [11.2, 11.8]) is calculated by the author from the 2018 Tobacco Use Supplement to the Current Population Survey

This puts additional strain on the cardiovascular system and causes chronic health conditions