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The former may be involved in fetal programing of adult disorders (Suter and Aagaard, 2012), whereas the latter may play a role in tissue-specific carcinogenesis (for example, cigarette smoke

The breath of cigarette smokers and users who have switched to alternative nicotine delivery products such as e-cigarettes and HTPs would be analyzed to identify potential biomarkers of halitosis and obtain quantitative measurement of halitosis-related compounds

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This only accounts to an estimate of 82.3 billion cigarettes

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