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In conditions such as asthma and COPD, mitochondrial dysfunction leads to increased mtROS production, which activates the NLRP3 inflammasome

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While tobacco health effects are widely explored and updated, recent studies on tobacco costs for society are lacking

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Additionally, both SHS exposure and its duration have been associated with p53 overexpression in feline oral squamous cell carcinomas, suggesting a possible role in tumorigenesis 51