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The oxygen carrying ability of the blood decreases due to the carbon monoxide absorbed into the blood while smoking

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Translocator protein is a marker of activated microglia in rodent models but not human neurodegenerative diseases

Since TLR4 deficiency eliminated tissue penetration and ROS production in systemic tissues and reduced the PM 2.5 influence on boosting peripheral Ly6C high cells (F4/80 + , CD11b + , and CD115 + ), it appears that these pathways play a role in mediating the effects of exposure (153)