inventor of tobacco James Albert Bonsack A medical history of smoking,

It is important to recognize that coughing and gagging are symptoms rather than standalone conditions

This has taken the form of a price war, verbal threats, private legal action by one company to force the closure of a competitors factory in Lesotho, attempted and successful assassinations, and the vandalism of the machinery of a factory as part of a dispute between two independent companies

Available from: Freeman TP, Groshkova T, Cunningham A, Sedefov R, Griffiths P, Lynksey MT

The two non-nicotine medications are: bupropion SR (sustained release), a non-nicotine medication that is thought to decrease the urge to smoke by affecting the same chemical messengers in the brain that are affected by nicotine

However, Dr Wang-Rodriguez stressed that the results may not replicate the processes in the human body, as the amount of vapour used was "similar to someone smoking for hours on end"