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The nitrosation of nicotine as a result of metabolism gives rise to TSNAs, where N-nitrosonornicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone are the two most predominant forms and have been classified as group 1 carcinogens

Industrially, benzene is useful to make ethylbenzene, a precursor to styrene

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Nicotine itself does not cause cancer

Smoking pipes A few of the advantages that smoking tobacco pipes has is the relaxation effect