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Among vapers, those who used fruit flavors or multiple flavors, as well as advanced refillable devices (often called "mods"), showed more changes in gene expression compared with other groups

Unlike transdermal patches, the cannabinoids in topical creams don't enter the bloodstream, but they do penetrate deep into the skin to produce local effects

Instead, manufacturers fought FDAs attempts to regulate them in that way, and won in federal appeals court