Shared Risk Factors Aging Cigarette smoking Physical inactivity How COPD Drives Cardiovascular Disease Persistent systemic inflammation endothelial dysfunction, platelet activation & pro-thrombotic state Impaired gas exchange arterial hypoxemia & myocardial hypoxia contractility, arrhythmias Lung hyperinflation venous return, compressed pulmonary vessels reduced cardiac output Exertional dyspnea reduced physical activity (often worsened by anxiety & depression) CV risk How CVD Worsens COPD Outcomes Alveolar & bronchial edema from LV dysfunction airflow limitation Post-capillary pulmonary hypertension Reduced skeletal muscle oxygen delivery further inactivity & deconditioning Take-home Message COPD is not just a lung disease
Starts out strong on initial light, but fates to the background in the first 1/4 and I could no longer detect it by the end
Don't clean with a hard object,avoid scratch the surface
The smokiness from the tobacco leaf and the rum hit you right away - the rum is very boozyas well as a hit of fresh neroli and lemon, but once the vanilla bean starts to peek through the whole composition rounds out with a welcome sweetness that makes the one of the most distinctive, and wearable, scents on this list
Chronic Obstructive Pulmonary Disease (COPD): A progressive disease that makes it increasingly hard to breathe
