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Direct interaction between Nrf2 and p21Cip1/WAF1 upregulates the Nrf2-mediated antioxidant response

Three to six months is standard because sermorelin's GH elevation is more gradual and cumulative

Currently, sex-specific pharmacokinetic data remain missing for a substantial number of approved drugs, and only a few drugs are prescribed with labeled sex-based dosage

Funding This work was supported by grants from the National Natural Science Foundation of China (NSFC Numbers 81672800, 81603009, 81673020, 81802632, and 82173830), Natural Science Foundation of Shaanxi (2020JQ-445), and the Key Research and Development Program of Shaanxi Province (2021SF-207, 2021SF-223, and 2022ZDLSF05-19)

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