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The lack of delta-agonist activity has been suggested to account for the observation that buprenorphine tolerance may not develop with chronic use

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It has been illegal for businesses to sell or supply disposable vapes in the UK since June 2025

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A case study of a 23-year-old e-cigarette user shows promising results for tapering e-cigarette use with the assistance of a pharmacist 81 , which suggests that different healthcare practitioners may play a role helping patients with gradually tapering off e-cigarettes