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The primary risks include increased hypoglycemia risk (especially with insulin or sulfonylureas), additive gastrointestinal symptoms such as nausea and diarrhea, and unknown effects on medication absorption due to tirzepatide's delayed gastric emptying

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Specifically, the SLC22 transporter protein family encompasses OAT, OCT, OCTN, and URAT1 [38]

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Mounjaro is a dual-agonist drug that targets both GLP-1 and GIP receptors