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However, analysis of Google search trends reveals nearly 10 times as many searches for these compounds in 2025 compared with 2020 and studies suggest that the number of gym-goers using performance-enhancing drugs has more than tripled since 2014

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If SGLT2i are used in those with eGFR 8%, then the addition of these agents is less likely to cause hypoglycemia but the patient should be counselled about the potential for hypoglycemia

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