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Interestingly, one study found that GLP-1R knockout mice were protected from high-fat diet-induced insulin resistance and had enhanced insulin-stimulated skeletal muscle glucose uptake, and these mice also exhibited enhanced action of insulin on hepatocytes as well as decreased hepatic and skeletal muscle triglyceride accumulation

The active molecule is the same

Since these products cause nausea or vomiting, they can lead patients or clinicians to reduce or stop insulin due to missed meals

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