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If you don't clean it regularly enough then mold will start growing on the filter which can cause an unpleasant odor when it comes into contact with warm air being blown out by your AC unit

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Support for the study was provided by the California Tobacco-Related Disease Research Grants Program Office of the University of California and the National Institute of Alcohol Abuse and Alcoholism

Quantitation of pyridyloxobutyl-DNA adducts in tissues of rats treated chronically with ( R )- or ( S )- N -nitrosonornicotine (NNN) in a carcinogenicity study