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Under normal conditions, 1-AR is primarily located in the cytoplasm of hepatocytes, whereas 2-AR is predominantly expressed on the cell membrane of hepatocytes 32

Magwenzi S, Woodward C, Wraith KS, Aburima A, Raslan Z, Jones H, McNeil C, Wheatcroft S, Yuldasheva N, Febbriao M, Kearney M, Naseem KM

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Meanwhile, we emphasized the ideal anti-osteoporotic property and individual achievability of methods like fecal microbiota transplantation, probiotic and prebiotic supplementation, and dietary pattern modification