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Abstract Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have shown promise in preclinical models of neurodegeneration, with emerging evidence suggesting these effects may be driven by modulation of neuroinflammation

Eli Lilly is still in the middle of phase three clinical trials on its oral drug, orforglipron, meaning it's likely to hit the market later

Hydration Changes : Weight loss medications can alter fluid balance, potentially affecting joint lubrication

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A multifaceted, chronic disease may need a multi-pronged, long-term, sustainable intervention, added Jaisinghani