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This study aims to investigate the hepatoprotective effects of NTZ utilizing a rat model of acute MTX-induced hepatotoxicity shedding some light on the mechanism of NTZ-mediated hepatoprotection with a focus on the possibility of modulation of oxidative stress, ER stress and apoptosis

Secondary analyses of the MAESTRO-NASH trial suggest that resmetirom retains efficacy in patients concomitantly using GLP-1 RAs, supporting the feasibility of combination approaches [71]

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